Detorsion of Wandering Spleen Causes Significant Hypersplenism Resulting in Thrombocytopenia and Spinal Cord Injury: A Case Report

Yui Innami et al.

INTRODUCTION: We report the case of a child who underwent splenectomy and developed marked thrombocytopenia after detorsion due to wandering splenic torsion.

Asymptomatic Splenic Infarction Following Total Gastrectomy: A Case Report

Atsuhito Takagi, et al.

INTRODUCTION: Splenic infarction is a disease that develops as a result of a thrombotic predisposition. Most areas of malperfusion are usually small and unnoticeable. However, when massive infarction occurs, it is often diagnosed after the onset of clinical symptoms, such as abdominal pain or fever. In contrast, asymptomatic postoperative extensive splenic infarction is occasionally observed. Although conservative management is generally the first-line treatment for splenic infarction, surgical intervention is indicated in cases complicated by splenic abscess or rupture. Some reports suggest that extensive splenic infarction may result in atrophy or complete loss of the spleen over time.

A Case of Spontaneous Regression of Primary Tumor after Adrenalectomy for Primary Lung Cancer with Synchronous Adrenal Metastasis

Hisaya Chikaraishi, et al.

INTRODUCTION: Adrenal metastasis from primary lung cancer is relatively common, occurring in approximately 5%–10% of clinical cases. Long-term survival can be achieved through surgical resection of adrenal metastases in addition to primary lesions. Spontaneous regression of cancer is defined as the partial shrinkage or complete disappearance of cancer following no treatment or treatment considered ineffective against cancer. Spontaneous regression of non-small cell lung cancer (NSCLC) is rare. Here, we describe a case of NSCLC with adrenal metastasis, in which the primary tumor exhibited spontaneous regression and was pathologically absent following surgical treatment of the metastatic lesion.

Resectable Pancreatic Adenocarcinomas following Neoadjuvant Chemotherapy with Gemcitabine Plus S-1: Two Case Reports of Opposite Oncological Outcomes

Masanobu Taguchi et al.

INTRODUCTION: Neoadjuvant gemcitabine plus S-1 (GS) therapy for resectable pancreatic cancer has been shown to prolong overall survival significantly compared with upfront surgery. Herein, we report two opposite cases of patients with resectable pancreatic cancer who underwent distal pancreatectomy after neoadjuvant GS therapy.

Simultaneous Resection of Esophageal Carcinosarcoma with Cancer of the Stomach and Transverse Colon: A Case Report

Kenichi Mizunuma, et al.

INTRODUCTION: Esophageal carcinosarcoma is a rare malignant neoplasm composed of both carcinoma and sarcoma components. Here, we report a case of esophageal carcinosarcoma in a patient with cancers of the transverse colon and stomach who underwent simultaneous resection of all 3 malignancies.

A Case of Solitary Fibrous Tumor of the Greater Omentum Incidentally Detected during Preoperative Evaluation for Thyroid Cancer

Rei Hatayama, et al.

INTRODUCTION: Solitary fibrous tumor (SFT) is a mesenchymal tumor and accounts for less than 2% of all soft tissue tumors. It is most commonly found in the pleura and has a relatively good prognosis.

A Case of Myoepithelioma-Like Tumor of the Vulvar Region after Removal of an Inguinal Tumor

Kei Urakami, et al.

INTRODUCTION: Myoepithelioma-like tumor of the vulvar region (MELTVR) is a mesenchymal neoplasm first reported in 2015 and typically develops from the inguinal to the vulvar regions of adult women.

A Case of Drug-Induced Pancytopenia due to Tamoxifen

Akari Takahashi et al.

INTRODUCTION: Tamoxifen (TAM) is a well-established treatment for hormone receptor-positive breast cancer with a known side-effect profile that includes hot flashes, genital bleeding, and diarrhea (0.1%–5%). Other notable side effects include liver damage, abnormal vaginal discharge, depression, dizziness, and headaches of unknown frequency. However, blood cell count reduction has not yet been reported as a side effect in Japan.

An Intrahepatic Cholangiocarcinoma Patient with von Willebrand Disease Successfully Treated with Robotic Hepatectomy under von Willebrand Factor Supplementation

Hiroto Chiba, et al.

INTRODUCTION: Von Willebrand disease (VWD) is the second most common inherited coagulation disorder, and appropriate perioperative management is necessary when considering major surgery. There are few reports of patients with VWD who have undergone hepatectomy, especially minimally invasive hepatectomy. To our knowledge, this is the first reported case of a patient with VWD who successfully underwent robotic hepatectomy with von Willebrand factor (VWF) and factor VIII (FVIII) supplementation.

A Case of Esophageal Retention Cyst with High Fluorodeoxyglucose Uptake on PET/CT Scan

Byonggu An, et al.

INTRODUCTION: Esophageal retention cysts are rare, benign lesions that can mimic submucosal tumors. Their clinical presentation and imaging characteristics may lead to diagnostic challenges, particularly when fluorodeoxyglucose-positron emission tomography/CT (FDG-PET/CT) shows increased uptake, raising suspicion of malignancy.

Mediastinoscopy-Assisted Esophagectomy as an Effective Treatment for IgG4-Related Esophageal Stenosis: A Case Report

Masazumi Sakaguchi, et al.

INTRODUCTION: Immunoglobulin G4-related disease (IgG4-RD) rarely involves the esophagus, typically causing stenosis that presents significant diagnostic and therapeutic challenges. Due to its rarity and its mimicry of other conditions, obtaining a definitive preoperative diagnosis can be difficult. This report details a case of IgG4-RD-induced esophageal stenosis with initial diagnostic ambiguity, which was successfully managed with mediastinoscopy-assisted esophagectomy (MAE), highlighting this minimally invasive approach in a patient with comorbidities.

Combined Arterial Reconstruction and Surgical Distal Venous Arterialization for Limb Salvage in Thromboangiitis Obliterans: A Case Report

Yuri Yoshida, et al.

INTRODUCTION: Thromboangiitis obliterans (TAO) has become increasingly uncommon in Japan due to declining smoking prevalence. However, in advanced cases with severely compromised distal vasculature, achieving durable limb salvage remains a formidable surgical challenge.