Breast Cancer Metastasis to the Upper Arm: A Rare Case and Review of the Literature

Yuka Nishimura, et al.

INTRODUCTION: Soft tissue metastasis of breast cancer is very rare. Specifically, metastasis to the upper arm has only been reported in 10 cases, including this one, to the best of our knowledge. Distant lymph node metastasis of breast cancer is also infrequent, with only one documented case of brachial lymph node metastasis.

Conversion Surgery via Laparoscopic Gastrectomy and Hepatectomy for Advanced Gastric Neuroendocrine Carcinoma with Extensive Liver Metastases: A Case Report

Shota Ishii, et al.

INTRODUCTION: Gastric neuroendocrine carcinoma (G-NEC) is a rare but highly aggressive malignancy that often presents with distant metastases and significantly worsens prognosis. Recent studies have suggested that conversion surgery after chemotherapy may improve outcomes in initially unresectable gastric cancers; however, evidence regarding its application in G-NEC remains limited. We report a rare case of advanced G-NEC with multiple liver metastases that was treated with R0 resection through conversion surgery after chemotherapy.

Thymoma with Intravascular Tumor Thrombus in the Left Brachiocephalic Vein: A Case Report

Taimei Tachibana, et al.

INTRODUCTION: Thymomas have the potential to locally invade and metastasize, occasionally infiltrating adjacent structures, such as the great vessels and the heart. Although direct extension is the primary mechanism of vascular invasion, rare cases of intravascular growth have also been reported.

Pulmonary Squamous Cell Carcinoma with Repeated Increases and Decreases in Size

Yuji Nozaka, et al.

INTRODUCTION: Spontaneous regression of cancer is rare. Although the underlying mechanism is unknown, immunological responses are thought to be involved.

Evaluation of Blood Flow in a Reconstructed Gastric Conduit by Thermography in Esophageal Cancer Surgery

Shuhei Ueno et al.

INTRODUCTION: A complication of gastrointestinal anastomosis is anastomotic leakage; the incidence of anastomotic leakage following esophageal cancer surgery remains high. Several factors contribute to anastomotic leakage; however, blood flow to the reconstructed organ is the most significant factor. Currently, indocyanine green (ICG) fluorescence is widely used for evaluating blood flow; however, several issues have been observed, including allergic reactions to the drug. We investigated the usefulness of thermography (TG) for gastrointestinal blood flow evaluation.

Laparoscopic Distal Gastrectomy for Duodenal Adenocarcinoma Located in a Duodenal Bulb Diverticulum: Report of a Rare Case

Masato Nishimuta et al.

INTRODUCTION: Duodenal adenocarcinomas are relatively rare. We report here a particularly rare case of duodenal adenocarcinoma that arose within a duodenal bulb diverticulum and was successfully managed surgically.

Inflammatory Response during Neoadjuvant Chemotherapy with Immune Checkpoint Inhibitors in a Patient with T3N1 Triple-Negative Breast Cancer: A Case Report

Kyoko Goda et al.

INTRODUCTION: Preoperative chemotherapy, including immune checkpoint inhibitors (ICIs), is widely accepted as the most likely treatment regimen to obtain a pathological complete response (pCR) in triple-negative breast cancer (TNBC). This case report presents a rare instance of a pCR in a patient with cT3N1M0 TNBC who underwent neoadjuvant chemotherapy (NAC) with ICIs.

Long-Term Survival Following Multimodal Therapy with Sunitinib and Surgery for Recurrent Duodenal Gastrointestinal Stromal Tumor

Manatsu Mizuno, et al.

INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors often driven by KIT or PDGFRA mutations. Sunitinib, a second-line tyrosine kinase inhibitor (TKI), is effective in imatinib-resistant cases, particularly those with secondary KIT mutations in the ATP-binding domain. However, resistance to sunitinib poses challenges, and evidence supporting surgery during sunitinib treatment remains limited.

Immune Checkpoint Inhibitor-Related Aortitis Treated with Nivolumab for Esophageal Squamous Cell Carcinoma

Norihiro Akimoto, et al.

INTRODUCTION: Although immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) are widely recognized, ICI-related aortitis is very rare and challenging to diagnose.

Perioperative Management of Single Lung Transplantation for a Chronic Obstructive Lung Disease Patient with Congenital Alpha2-Plasmin Inhibitor Deficiency

So Miyahara et al.

INTRODUCTION: Coagulation disorders can lead to massive perioperative bleeding regardless of the type of surgery. Their preoperative identification is essential (from a complete history of bleeding tendency) and steps should be taken to mitigate such complications at the time of surgery. Alpha2-plasmin inhibitor (α2-PI) deficiency is a rare congenital coagulation disorder resulting in activation of fibrinolysis and requiring specific treatment with antifibrinolytic agents. Lung transplantation has not been previously reported in a patient with α2-PI deficiency.

A Surgical Case of Synchronous Double Cancer of the Pancreatic Tail and the Distal Bile Duct

Atomu Suzuki, et al.

INTRODUCTION: In recent years, there have been many reports of cases of double cancer. This is due to improvements in diagnostic techniques and treatment methods for cancer and the extension of average life expectancy. However, there are few reports of bile duct cancer and pancreatic cancer occurring together.

Neoadjuvant Chemotherapy for Stage II Rectal Cancer Diagnosed in the Second Trimester of Pregnancy: A Case Report

Haruka Kubo, et al.

INTRODUCTION: The onset of colorectal cancer during pregnancy is rare, and no standard treatment has been established. In this report, we present the case of a woman with clinical stage II rectal cancer diagnosed in the second trimester, in which neoadjuvant chemotherapy was administered, followed by delivery once fetal development was sufficiently advanced, and surgery was performed afterward.